Letrozole, also commonly referred to as an oral aromatase inhibitor that is usually used in treating hormonally responsive breast cancer after undergoing surgery. This drug was approved by the FDA for use in post-menopausal women who exhibit types of breast cancer that are receptor positive.
Letrozole has very many uses, most of which have been discovered recently. Aside from its use as an inhibitor in breast cancer treatment, it also has an off label use. Its major off label use is as a fertility drug due to its ability to simulate the ovaries. It is also commonly used in the treatment of gynecomastia.
Similar to all aromatase inhibitors, Letrozole works through binding to aromatase enzyme. This in turn prevents the release of estrogen. In scientific terms, it is referred to as a type II inhibitor. It is one of the most powerful aromatase inhibitors available in the market.
Since this inhibitor is very powerful, we can put it into use to combat emergency situations in the body, for instance when estrogen related sides get out of control. In some cases, an anabolic steroid user uses a compound such as dianabol or testosterone, they are likely to aromatize in the body and convert into estrogen.
This may result in a number of estrogen related side effects such as water retention, which has a domino effect and may end up affecting your libido, blood pressure, sleep and energy levels. As a result of excessive estrogen in the body, you may also develop gynecomastia. Which is a condition if left untreated may require invasive and expensive surgery.
Gynecomastia is a common disorder of the human endocrine system whereby there occurs a non-cancerous increase in the size of the breast tissue of a man. It is possible to treat this condition with Letrozole. As earlier stated, Letrozole is one of the most powerful aromatase inhibitors in the world. Studies show that it reduces the levels of estrogen very quickly and sharply.
In case you have neglected to an aromatase inhibitor and find yourself in desperate shape, they can always turn to Letrozole for a quick gynecomastia cure. When it comes to gynecomastia, there is nothing more effective than Letrozole.
Many people tend to confuse Letrozole and Aromasin-Arimidex. The truth of the matter is that they could not be further from the truth. Letrozole is not a suicide aromatase inhibitor, unlike Aromasin-Arimidex. This means that it does not disable the aromatase enzyme permanently.
Like all drugs however, Letrozole has its own side effects. In the body building world, there is such a thing as too much. When it comes to aromatase inhibitors, Letrozole definitely falls into the same bill. Even though estrogen is view as a female hormone, it is vital for males for they system to function properly. After all, estrogen is vital in the growth of muscles.
Having inadequate levels of estrogen in the body may cause depression, lower libido and affect your mood. Since this drug is very powerful when it comes to lowering estrogen levels, you ought to be very careful not to abuse it.